U.S. researchers found that one of the enzymes associated with the collection of fat in the human body at the same time also play a positive role in maintaining the health of the skin and hair.
The researchers discovered that mice that have hired them to conduct such a study become at its lack of this enzyme known as DGAT1, become frail, and resistant to diet that leads to infection with obesity, and become more sensitive to insulin and leptin, and infected oddly in the process of growth of thyroid-feeding as well as the skin.
When the researchers used the Gladstone Institute of the American Heart and blood vessels in a manner of genetic engineering to clear the enzyme by a group of mice, they found that his absence causes increased levels of retinoic acid (RA) significantly in the skin, leading to hair loss.
Robert Varese said, the principal investigator and co-author of the study: “We have for some time studying the enzymes that cause the increase in the amount of triglycerides.
And found that one of these enzymes act as the main organizer of the movements of retinoic acid in the skin. ”
The researchers explained that retinoic acid, which comes from vitamin A (retinol) is used in the treatment of skin disorders, such as acne, psoriasis and hair loss as well as some types of cancer, but Sam very much and must be controlled carefully and take care of.
They noted that the rat-free enzyme “DGAT1”, their skin is very sensitive to retinol. It also causes the loss of this enzyme is also presented in the incidence of hair loss. It can prevent both of these effects by preventing the mouse from a source of retinol in their diets.
The results of this study have been published in the Journal of Biological Chemistry that the enzyme “DGAT1” is possible that converts retinol to form relatively inert storage.
Without this enzyme, this ability is lost, and any additional quantity of retinol can be found in the skin can be transformed to retinoic acid.